Infection (infectious colitis)Autoimmune disease (ulcerative colitis, Crohn’s disease)Lack of blood supply (ischemic colitis) Diverticulosis (diverticulitis)Other serious conditions
Colitis can result in symptoms that are similar to those of irritable bowel syndrome (IBS). This raises the question: Is there an overlap or connection between IBS and colitis?
IBS vs. More Serious Causes of Intestinal Symptoms
Even though IBS can significantly impair your quality of life, it is usually not considered a serious illness, and it doesn’t lead to life-threatening complications.
However, be sure to talk to your healthcare provider if you experience any symptoms that could point to a more serious condition, including:
Severe painSignificant fatigueLack of appetiteNew, long-lasting constipation or diarrhea (greater than six to 12 weeks) Shortness of breathBlood in stoolChange in quality of stool (thin, “worm-like” stools)Weight lossFeverMouth ulcers
Ulcerative Colitis and IBS
Ulcerative colitis is one of the two inflammatory bowel diseases (IBDs). Symptoms shared by ulcerative colitis and IBS include:
Chronic abdominal pain and cramping Diarrhea Mucus in stool Bowel urgency
Ulcerative colitis is a more serious condition than IBS. Other symptoms of ulcerative colitis that aren’t present in IBS include:
Blood in the stool Fever Significant loss of appetite (more than can be explained by food avoidance for fear of setting off symptoms) Visible signs of ulceration in the lining of the large intestine
Microscopic Colitis and IBS
Microscopic colitis is a disease in which a person experiences chronic, watery diarrhea. The disease differs from IBS in that signs of infection can be seen when intestinal cells are examined under a microscope.
Shared symptoms of microscopic colitis and IBS are:
Abdominal pain and/or cramps Chronic diarrhea Fecal incontinence
Symptoms unique to microscopic colitis include:
NauseaWeight loss
Infectious Colitis and IBS
Infectious colitis is an illness that is caused by an infectious agent, such as:
CampylobacterEscherichia coliSalmonellaShigellaClostridioides difficile
The symptoms of infectious colitis are quite different from those of IBS, and include:
Bloody diarrheaChillsFever
Overlap Between IBD and IBS
Although the two disorders have traditionally been seen as distinct in terms of both presentation and cause, some researchers are putting forth theories that perhaps the two diagnoses of IBS and IBD are actually at different ends of the same spectrum.
Some studies have shown that people who have IBS are at higher risk of eventually being diagnosed with IBD (ulcerative colitis or Crohn’s disease). One group of researchers found that this higher risk may be associated with having experienced infectious gastroenteritis (stomach “flu” caused by an infectious bacteria or virus).
Inflammation in IBS
Although the diagnosis of IBS requires that there be no visible signs of inflammation, researchers are increasingly finding evidence that inflammation does in fact play a role in the symptoms of IBS.
This inflammation in the cells lining the large intestine is not visible, as is the case with ulcerative colitis, nor can it be seen with a microscope, as is the case with microscopic colitis.
Instead, this inflammation is considered to be low-grade and requires an in-depth examination of tissue to identify its presence.
Researchers are working to discover further information about the role of inflammation to open up the promise of more effective treatment options for IBS.
A Word From Verywell
It’s imperative to monitor the signs and symptoms of IBS or any other digestive disorder you may be struggling with. If you notice any significant changes, talk to your healthcare provider and get tested so you can treat the problem and feel better.
