This article discusses the types and causes of itchy lupus rashes on the legs, treatment options, and when to see a healthcare provider.
Types of Lupus Rash
Lupus can cause several types of rashes, including some specific to certain disease forms. Three common types of lupus are defined by cutaneous (skin) involvement. The four main lupus types are:
Systemic lupus erythematosus (SLE): May lead to symptoms in one or more of your bodily systems, including the skin Acute cutaneous lupus (ACL): Usually appears alongside SLE Chronic cutaneous lupus (CCL): Persistent skin involvement and can appear alongside SLE Subacute cutaneous lupus (SCL): Can appear alongside SLE
If you have SLE, you may be prone to lupus-associated skin problems.
Acute Cutaneous Lupus
One of the most common skin symptoms of lupus is a malar rash. It’s referred to as a butterfly rash when it’s across the cheeks and nose.
Malar rash is a type of ACL that is commonly seen in SLE. About 50% of people with lupus will develop a malar rash. While most commonly associated with lupus, a malar rash can be seen in other disorders, such as cellulitis, rosacea, and erysipelas.
Fatigue despite adequate sleepJoint, muscle, and tendon pain and inflammationPuffiness in the hands and feet and around the eyesRecurring low-grade feverHair lossAnemiaDry eyes and mouthDigestive problemsRaynaud’s disease (causes fingers and toes to be cold and numb)
Many other symptoms are possible, depending on what organs or systems the disease targets.
Lupus Rash Treatment
Lupus rash treatments generally involve topical treatment (applied to the skin), oral medication (taken by mouth), and avoiding ultraviolet (UV) light.
Topical Treatment
Topical treatment includes corticosteroid creams. These are powerful anti-inflammatory medications. The strength that’s usually needed is only available with a prescription and should be used under the supervision of a healthcare provider.
Other topical anti-inflammatory medications may be used to avoid the possible side effects of corticosteroids.
Oral Medication
The medications for lupus-related skin problems may also be prescribed for the full range of lupus symptoms. They include:
Antimalarial drugs: Plaquenil (hydroxychloroquine), chloroquine Immunosuppressants: Trexall (methotrexate), Gengraf (cyclosporine), CellCept or Myfortic (mycophenolate mofetil) Oral corticosteroids: For when topical steroids aren’t effective enough
Avoiding UV Light
Many lupus-related skin problems are exacerbated by sunlight. Avoiding UV light may involve staying out of direct sunlight, wearing strong sunscreen, such as with a sun protection factor of 50 (SPF 50), when outside, and wearing protective clothing. Take special care to keep out of the sun when you have an active rash.
When to See a Healthcare Provider
Anytime you have an unexplained rash, you should see a healthcare provider. Get immediate help if it is:
Especially itchy or painfulCovering much of your bodySpreading quicklyBlisteringShows any signs of infection (swelling, crusting, pain, heat, red streaks, yellow or green pus)
If you’re diagnosed with lupus and notice any possible new skin involvement, let your rheumatologist or dermatologist know right away.
Summary
Lupus can cause a variety of rashes, some of which can affect the legs and be itchy. A malar rash is typical of SLE and acute cutaneous lupus. Chronic cutaneous lupus often causes a discoid rash. Subacute cutaneous lupus can cause two types of rash, one of which can be mistaken for psoriasis. Treating lupus rashes involves topical creams, medications, and avoiding sunlight. Contact your healthcare provider if you have a new, undiagnosed, or worsening rash.
A Word From Verywell
An itchy lupus rash, especially on large areas of your body, such as the legs, can be uncomfortable and can significantly impact your quality of life. Fortunately, there are treatment options that can make lupus-related skin problems manageable.
There was an error. Please try again.
